Study Design Update of the Off-pump versus On-pump Coronary Artery Bypass Grafting in Frail Patients: FRAGILE Trial

Omar Asdrubal Vilca Mejia¹;Fabiane Letícia de Freitas¹;Bianca Meneghini¹;Maurilio Onofre Deininger²;Rodrigo Segalote³;Felipe Consentino³;Mauricio Guerrieri⁴;Alexandre Ciappina Hueb⁴;Fernando Ribas⁵;Rodrigo Moreira Castro⁵;Luís Roberto Palma Dallan¹;Pedro GM de Barros e Silva⁶;Renato D. Lopes^6,7;Luiz Augusto Ferreira Lisboa¹;John Puskas⁸;Fabio B Jatene¹

DOI: 10.21470/1678-9741-2025-0199 e20250199 Publish in: July 31 2025